訂購信息：
品牌 | 貨號 | 品名 | 規格 | 目錄價 | 備注 |
R&D SYSTEMS | 240-B-002 | Recombinant Human TGF-beta 1 Protein | 2ug | 3502 | 現貨 |
R&D SYSTEMS | 240-B-010 | Recombinant Human TGF-beta 1 Protein | 10ug | 10938 |
介紹：
作為胞外信號分子，TGF-beta1蛋白在多種細胞中進行表達，并作為胞外信號分子參與免疫功能，細胞增殖和細胞分化等生物學過程。1985年，作為公司推出的第一個科研試劑產品，也是全球第一家將該產品進行商業化生產的產品，R&D Systems成功上市了TGF-beta1蛋白。
Purity | >97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie? Blue Staining. |
Endotoxin Level | <0.10 EU per 1 μg of the protein by the LAL method. |
Activity | Measured by its ability to inhibit the IL-4-dependent proliferation of HT 2 mouse T cells. Tsang, M.et al. (1995) Cytokine 7:389. The ED50 for this effect is 0.04-0.2 ng/mL. The specific activity of Recombinant Human TGF-beta 1 is approximately 2.5 x 104 U/μg, which is calibrated against human TGF beta 1 Standard (NIBSC code: 89/514). |
Source | Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein Ala279-Ser390 |
Accession # | P01137 |
N-terminal Sequence Analysis | Ala279 |
Structure / Form | Disulfide-linked homodimer |
Predicted Molecular Mass | 12.8 kDa (monomer) |
SDS-PAGE | 12 kDa, reducing conditions |
24 kDa, non-reducing conditions |
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